Journal of Cutaneous and Aesthetic Surgery

LETTER TO THE EDITOR
Year
: 2021  |  Volume : 14  |  Issue : 4  |  Page : 458--461

Dermoscopic evaluation of CO2 laser treatment in the scar of lupus vulgaris


Yasmeen Jabeen Bhat, Nahida Nabi, Amanullah Daing 
 Postgraduate Department of Dermatology, Venereology, and Leprosy, GMC Srinagar, University of Kashmir, Jammu and Kashmir, India

Correspondence Address:
Dr. Yasmeen Jabeen Bhat
Postgraduate Department of Dermatology, Venereology, and Leprosy, GMC Srinagar, University of Kashmir, Jammu and Kashmir.
India




How to cite this article:
Bhat YJ, Nabi N, Daing A. Dermoscopic evaluation of CO2 laser treatment in the scar of lupus vulgaris.J Cutan Aesthet Surg 2021;14:458-461


How to cite this URL:
Bhat YJ, Nabi N, Daing A. Dermoscopic evaluation of CO2 laser treatment in the scar of lupus vulgaris. J Cutan Aesthet Surg [serial online] 2021 [cited 2022 Aug 14 ];14:458-461
Available from: https://www.jcasonline.com/text.asp?2021/14/4/458/337604


Full Text



Sir,

Lupus vulgaris (LV) is a chronic, progressive, secondary cutaneous form of tuberculosis that heals with scarring leading to cosmetic and psychological morbidity when present on the exposed sites. We hereby report a case of LV over nose complicated by scarring following treatment with anti-tubercular therapy (ATT). Six sessions of fractional CO2 laser resurfacing for the post-treatment atrophic scar resulted in excellent response clinically that was documented dermoscopically.

LV is a chronic, indolent form of cutaneous tuberculosis seen in patients with moderate-to-high immunity that classically presents as papulonodular lesions coalescing to form plaques with areas of progression as well as scarring. Face is a common site including the nose, though septal perforation is rare.[1] The resultant atrophic scarring following ATT may lead to deformity and mutilation along with fibrotic contractures.[2]

Treatment options for managing such scars are limited. Fractional carbon dioxide (10,600 nm) laser resurfacing has been used in the treatment of atrophic scars with varying degrees of success. It is supposed to work by stimulating collagen production in the dermis and by dermal remodeling of collagen fibers.[3]

A 12-year-old child presented with history of elevated lesion over nose since 1 year. It started with a single papule on ventral aspect of nasal tip which gradually enlarged and progressed in due course of time. Patient had no significant history of trauma at the site, systemic symptoms, or past history of pulmonary tuberculosis. However, there was past history of pulmonary tuberculosis in a family member. He had received BCG vaccination at birth.

General physical and systemic examination were normal. Cutaneous examination showed well-defined erythematous and mildly scaly plaque of around 3 cm × 2 cm in size, involving right side of nasal tip with central brownish crust [Figure 1]. On diascopy, apple jelly nodules were seen in the center. Patient had firm and non-tender right submandibular lymphadenopathy. Nasal septum, lips, and oral mucosa were normal. Anterior rhinoscopy findings were normal.{Figure 1}

Dermoscopy ruled out verruca vulgaris and showed yellowish to orangish structureless areas, with linear branching vessels, reticular white streaks on an erythematous background favoring granulomatous pathology [Figure 1A]. Erythrocyte sedimentation rate was 30 mm/h. Mantoux test with one tuberculin unit of PPD RT23 was positive with 23 × 18 mm diameter erythema and induration after 48 h. Fine-needle aspiration cytology from the submandibular lymph nodes demonstrated tuberculoid granulomas with acid fast bacilli (AFB). Histopathology from the cutaneous plaque was consistent with LV [Figure 2]. Patient was started on category I ATT, DOTS regimen for 6 months after which he showed remarkable improvement and significant resolution of his lesions with atrophic scarring.{Figure 2}

After 1 year of follow-up post-treatment, in view of an atrophic scar at the site of the lesion, that was cosmetically unpleasant for the patient, fractional CO2 laser resurfacing was planned [Figure 3]. On dermoscopy, atrophy with long arborizing telangectasias on a yellow to golden background and milia-like cyst were seen [Figure 3A].{Figure 3}

Fractional CO2 laser sessions were done every 4 weeks for first four sessions (stamped mode, energy 25 mJ/cm2, PPA 64, F 50), and last two sessions were done 6 weeks apart with increased fluence at each session. Improvement of the lesion was noticed without any adverse effects [Figure 4][Figure 5][Figure 6]. Post-laser treatment dermoscopic features showed few milia-like cysts and peripheral telangectasia that diminished progressively with the laser sessions [Figure 4]A and [Figure 5]A.{Figure 4} {Figure 5} {Figure 6}

Dermoscopy helps in assessing the response to treatment in the granulomatous disorders. Dermoscopy of early plaque of LV shows yellowish orange discoloration in the background along with milia-like cysts and white reticular streaks with numerous broad and long arborizing telangectasias. The resolving plaque of LV shows variety of vascular patterns with peripheral telangectasias and decreased erythema and decreased hue of orange background.[4],[5]

In our case, fractional CO2 laser was used in the management of atrophic scar left after treatment with ATT, six sessions of fractional CO2 lasers were done, 4–6 weeks apart with increased fluence on each session, showing a marked improvement in the lesion. Dermoscopy after laser treatment showed resolving erythema with few peripheral telangectasias and reduced milia-like cysts.

To conclude, fractional laser resurfacing with CO2 laser offers a well-tolerated and effective treatment option in atrophic scars of LV, and dermoscopy offers a good tool for the assessment of treatment response. It may be utilized for scarring left after other granulomatous diseases.

Declaration of patient consent

The authors certify that they have obtained all appropriate patient consent forms. In the form, the patient(s) has/have given his/her/their consent for his/her/their images and other clinical information to be reported in the journal. The patients understand that their names and initials will not be published and due efforts will be made to conceal their identity, but anonymity cannot be guaranteed.

Financial support and sponsorship

Nil.

Conflicts of interest

There are no conflicts of interest.

References

1Garg A, Wadhera R, Gulati SP, Singh J Lupus vulgaris of external nose with septal perforation—A rarity in antibiotic era. Indian J Tuberc 2010;57:157-9.
2James WD, Berger TG. Mycobacterial diseases. In: Elston DM, Andrews GC, editors. Andrew’s diseases of the skin. 12th ed. Philadelphia, PA: Elsevier;2016. p. 332.
3Alster TS, Tanzi EL, Lazarus M The use of fractional laser photothermolysis for the treatment of atrophic scars. Dermatol Surg 2007;33:295-9.
4Errichetti E, Stinco G Dermoscopy in general dermatology: A practical overview. Dermatol Ther (Heidelb) 2016;6: 471-507.
5Lallas A, Argenziano G, Apalla Z, Gourhant JY, Zaballos P, Di Lernia V, et al. Dermoscopic patterns of common facial inflammatory skin diseases. J Eur Acad Dermatol Venereol2014;28:609-14.