Journal of Cutaneous and Aesthetic Surgery
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Year : 2013  |  Volume : 6  |  Issue : 3  |  Page : 155-157

Aggressive curettage-cryosurgery for human papillomavirus-16 ssociated subungual squamous cell carcinoma in situ

Dermatology Clinic, Läkarhuset, Gothenburg, Sweden

Correspondence Address:
Bo Clarence Stenquist
Department of Dermatology and Venereology, Sahlgrenska University Hospital, SE 41345 Gothenburg
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0974-2077.118417

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Squamous cell carcinoma (SCC) in situ is an uncommon tumour of the nail unit. Mohs micrographic surgery or wide surgical excision are often the preferred treatments. As an alternative therapy two patients with human papillomavirus (HPV)-16 associated SCC in situ were treated by curettage-cryosurgery. After a careful curettage with different-sized curettes freezing with liquid nitrogen in a double freeze-thaw was performed. Both patients were treated successfully and healed completely within 3 months. No adverse events were observed during a follow-up of at least 5 years and no recurrences were noted. Curettage-cryosurgery might be a safe and non-resource-demanding alternative treatment for patients with subungual SCC in situ.

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