Journal of Cutaneous and Aesthetic Surgery

ORIGINAL ARTICLE
Year
: 2017  |  Volume : 10  |  Issue : 1  |  Page : 3--7

Autologous platelet-rich fibrin matrix in non-healing trophic ulcers in patients with Hansen's disease


Umashankar Nagaraju, Priya K Sundar, Priyanka Agarwal, Belliappa P Raju, Mahesh Kumar 
 Department of Dermatology, Rajarajeswari Medical College and Hospital, Bengaluru, Karnataka, India

Correspondence Address:
Umashankar Nagaraju
Department of Dermatology, Rajarajeswari Medical College and Hospital, Kambipura, Mysore Road, Bengaluru, Karnataka
India

Background: Non-healing trophic ulcers in Hansen's disease patients is one of the major causes for disability. It has been shown that autologous platelet-rich fibrin matrix (PRFM) is effective in healing chronic non-healing leg ulcers. Aim: The objective of this study is to demonstrate the efficacy of autologous platelet-rich fibrin matrix (PRFM) in non-healing trophic ulcers in patients treated for Hansen's disease. Design: A prospective study. Setting: An institution-based clinic. Participants: Seven treated patients with Hansen's disease, with a mean age of 38.33 years, with nine non-healing trophic ulcer of more than 6 weeks duration. Measurements: Photographs were taken before treatment and at every subsequent sitting. Area and volume were calculated at baseline and every subsequent sitting till the closure was achieved. Materials and Methods: The healthy ulcers were treated with PRFM at weekly intervals, repeated once a week for a maximum of five sittings as per requirement. Results: The mean percentage improvement in the area was 93.52%, and volume was 97.74% at the end of the second sitting. All ulcers closed by a maximum of five sittings. No adverse events were noted. Conclusion: PRFM for the treatment of trophic ulcers in treated patients with Hansen's disease is a feasible, safe, simple and inexpensive method.


How to cite this article:
Nagaraju U, Sundar PK, Agarwal P, Raju BP, Kumar M. Autologous platelet-rich fibrin matrix in non-healing trophic ulcers in patients with Hansen's disease.J Cutan Aesthet Surg 2017;10:3-7


How to cite this URL:
Nagaraju U, Sundar PK, Agarwal P, Raju BP, Kumar M. Autologous platelet-rich fibrin matrix in non-healing trophic ulcers in patients with Hansen's disease. J Cutan Aesthet Surg [serial online] 2017 [cited 2020 Mar 29 ];10:3-7
Available from: http://www.jcasonline.com/article.asp?issn=0974-2077;year=2017;volume=10;issue=1;spage=3;epage=7;aulast=Nagaraju;type=0