Journal of Cutaneous and Aesthetic Surgery

CORRESPONDENCE
Year
: 2016  |  Volume : 9  |  Issue : 1  |  Page : 43--45

An unusual presentation of piloleiomyoma


Aditya Kumar Bubna, Mahalakshmi Veeraraghavan, Sankarasubramanian Anandan, Leena Dennis Joseph 
 Department of Dermatology, Sri Ramachandra University, Chennai, Tamil Nadu, India

Correspondence Address:
Aditya Kumar Bubna
Department of Dermatology, Sri Ramachandra University, Porur, Chennai - 600 116, Tamil Nadu
India




How to cite this article:
Bubna AK, Veeraraghavan M, Anandan S, Joseph LD. An unusual presentation of piloleiomyoma.J Cutan Aesthet Surg 2016;9:43-45


How to cite this URL:
Bubna AK, Veeraraghavan M, Anandan S, Joseph LD. An unusual presentation of piloleiomyoma. J Cutan Aesthet Surg [serial online] 2016 [cited 2020 Jan 22 ];9:43-45
Available from: http://www.jcasonline.com/text.asp?2016/9/1/43/178554


Full Text

Dear Editor,

Piloleiomyomas are benign tumors arising from the arrector pili muscle of hair follicles. They usually present between the second and third decade of life. [1] Predominantly, these tumors are located over the trunk and extremities, range in size between 2 mm to 2 cm, and are painful and firm in consistency. [2]

Our patient was a 45-year-old gentleman who presented to the Department of Dermatology with chief complaints of nodular skin lesions over the left upper arm since the past 7 years. It began as a singular, small pea-sized lesion that gradually progressed to reach the current status. Lesions were asymptomatic, the major cause of concern being cosmetic disfigurement. Clinical examination revealed the presence of around 15 nodules over the left upper arm ranging from 5 cm × 4 cm × 6 cm to 1 cm × 2 cm × 2 cm in size [Figure 1]. They were nontender on palpation and demonstrated a soft-rubbery consistency. A skin biopsy from one of the nodules revealed a normal epidermis, with poorly circumscribed interlacing smooth muscle fibers located in the dermis [Figure 2]. On higher magnification these fibers were individually composed of eosinophilic cytoplasm with an elongated eel-like nuclei [Figure 3]. Immunohistochemistry for smooth muscle actin (SMA) was positive [Figure 4]. However, S100 and Ki67 staining were negative [Figure 5] and [Figure 6]. With these findings a diagnosis of cutaneous leiomyoma was made. The patient was counselled regarding his treatment. However, he declined any surgical intervention.{Figure 1}{Figure 2}{Figure 3}{Figure 4}{Figure 5}{Figure 6}

Painless piloleiomyoma has not been a commonly encountered entity. A thorough literature search revealed only three case reports manifesting the painless display of piloleiomyoma. [3],[4],[5] Interestingly, in all these three cases piloleiomyoma presented as a solitary nodule, a feature dissimilar to our case, which presented as multiple nodules. Other salient features of the previous three cases including ours have been summarized in [Table 1].{Table 1}

With evaluation of our case and study of previous reported cases of painless piloleiomyoma, the authors would like to highlight that the painless quality of these lesions are not only a rarity, but painless leiomyomas are usually accompanied by other atypical findings that need vigilant identification. As far as treatment is concerned, surgical excision is the only available therapeutic modality at present, and given the high recurrence rate after surgery, this line of therapeutic intervention would not be practical with existent multiple nodules. To conclude, further exploration in the emergence of a concrete therapeutic modality in this setting is needed, as this domain still remains vastly unexplored.

Financial support and sponsorship

Nil.

Conflicts of interest

There are no conflicts of interest.

References

1Jimena NM, Marcela LM, Carolina LP, Cañadas NG, Castellanos Posse ML, Marchesi C, et al. Atypical leiomyoma: An unusual variant of cutaneous pilar leiomyoma. Dermatol Online J 2009;15:6.
2Raj S, Calonje E, Kraus M, Kavanagh G, Newman PL, Fletcher CD. Cutaneous pilar leiomyoma: Clinicopathologic analysis of 53 lesions in 45 patients. Am J Dermatopathol 1997;19:2-9.
3Pileri A, Ghetti PL, Neri I, Raone B, Ciabatti S, Reggiani C, et al. Atypical piloleiomyoma of the face presenting with central ulceration. Dermatol Reports 2011;3:e50.
4Bhaskar S, Jaiswal AK, Madhu SM, Santosh K. Unusual presentation of cutaneous leiomyoma. Indian J Dermatol 2014;59:634.
5Harford RR, Vidmar DA, Cobb MW, Miller ML. An atypical piloleiomyoma presenting as a nonhealing ulcerated nodule. Cutis 1996;57:168-70.