Journal of Cutaneous and Aesthetic Surgery
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INNOVATION
Year : 2020  |  Volume : 13  |  Issue : 1  |  Page : 38-42

Autologous smashed follicular dermal graft with epidermal cell suspension in chronic nonhealing leg ulcers


Department of Dermatology, Venereology and Leprology, RajaRajeswari Medical College and Hospital, Bengaluru, Karnataka, India

Correspondence Address:
Pranami Kashyap
Department of Dermatology, Venereology and Leprology, RajaRajeswari Medical College and Hospital, Mysore Road, Bengaluru 560074, Karnataka.
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/JCAS.JCAS_105_19

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Wound healing is a multifaceted process. Restoration of the epithelium may occur either by migration of activated epithelial keratinocytes from the adjoining epithelium or by centrifugal migration of putative stem cells found in the bulge region of the hair follicle. Dermal collagen and glycosaminoglycans also play a key role in laying down the scaffold for vascular in-growth and population of the matrix with host fibroblasts. Despite the availability of a wide range of treatment modalities, chronic nonhealing leg ulcers remain a therapeutic challenge and cause significant patient morbidity. Hence, there is a further need to develop novel techniques which would be effective, safe, easily available, and affordable for the patient.


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