Journal of Cutaneous and Aesthetic Surgery
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REVIEW ARTICLE
Year : 2016  |  Volume : 9  |  Issue : 3  |  Page : 139-144

Retinoids: literature review and suggested algorithm for use prior to facial resurfacing procedures


Department of Surgery, Section of Plastic and Reconstructive Surgery, University of Michigan Health Systems, Ann Arbor, Michigan, USA

Correspondence Address:
Robert H Gilman
Section of Plastic Surgery, 2130 Taubman Center, SPC 5340, 1500 East Medical Center Drive, Ann Arbor, MI 48109
USA
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0974-2077.191653

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Vitamin A-containing products have been used topically since the early 1940s to treat various skin conditions. To date, there are four generations of retinoids, a family of Vitamin A-containing compounds. Tretinoin, all-trans-retinoic acid, is a first-generation, naturally occurring, retinoid. It is available, commercially, as a gel or cream. The authors conducted a complete review of all studies, clinical- and basic science-based studies, within the literature involving tretinoin treatment recommendations for impending facial procedures. The literature currently lacks definitive recommendations for the use of tretinoin-containing products prior to undergoing facial procedures. Tretinoin pretreatment regimens vary greatly in terms of the strength of retinoid used, the length of the pre-procedure treatment, and the ideal time to stop treatment before the procedure. Based on the current literature and personal experience, the authors set forth a set of guidelines for the use of tretinoin prior to various facial procedures.


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