Journal of Cutaneous and Aesthetic Surgery
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ORIGINAL ARTICLE
Year : 2011  |  Volume : 4  |  Issue : 1  |  Page : 29-32

Nevus depigmentosus treated by melanocyte-keratinocyte transplantation


National Center for Vitiligo and Psoriasis, Olaya District, Tahlia Street, Riyadh, Saudi Arabia

Correspondence Address:
Sanjeev V Mulekar
National Center for Vitiligo and Psoriasis, Post Box 300320, Olaya District, Tahlia Street, Riyadh - 11372
Saudi Arabia
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0974-2077.79185

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Background : Nevus depigmentosus is a congenital, nonprogressive hypopigmented disorder. Various therapeutic methods have been attempted to repigment nevus with variable results. Objective : The objective of this study is to report our experience of treatment of nevus depigmentosus with a combination of noncultured melanocyte-keratinocyte transplantation (MKTP) and excimer laser sessions. Materials and Methods : Six patients (male 1, female 5) of nevus depigmentosus were treated with a combination of noncultured melanocyte-keratinocyte transplantation and excimer laser. One patient was lost to follow-up. Remaining five patients were observed for a period ranging from 7 to 30 months. Results : Two patients responded poorly to MKTP. The remaining three patients responded with repigmentation ranging from 80% to 100% but the quality of repigmentation was unsatisfactory in two of them. Conclusion : Though repigmentation of nevus depigmentosus is possible by grafting techniques, the results are inconsistent and recurrence is possible.


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