Journal of Cutaneous and Aesthetic Surgery
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ORIGINAL ARTICLE
Year : 2011  |  Volume : 4  |  Issue : 1  |  Page : 23-28

Autologous non-cultured basal cell-enriched epidermal cell suspension transplantation in vitiligo: Indian experience


Skin Laser Center, New Delhi, India

Correspondence Address:
Munish Paul
Skin Laser Center, New Delhi
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0974-2077.79183

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Introduction : Autologous non-cultured basal cell-enriched epidermal cell suspension transplantation is a simple yet effective cell-based therapy for vitiligo. Materials and Methods : This report is a retrospective analysis of 58 patients who were operated between December 2003 and August 2006 and were under follow-up for at least 2 years. Nine patients did not come for follow-up, and were excluded. At the time of transplantation all patients were having stable disease for at least 1 year. Epidermal cell suspension transplantation was done using Mulekar's method. Repigmentation was assessed and classified into excellent (>90% repigmentation), good (70-89%), fair (30-69%) and poor (<30%). Results : Of the 49 patients who came for follow-up, 32 (65%) had excellent (>90%) repigmentation; 9 (18%) had good (70-89%); 4 (8%) had fair (30-69%) and 4 (8%) patients had poor (<30%) repigmentation. During the follow-up, eight patients(16%) showed relapse of the disease. Conclusion : Autologous noncultured basal cell-enriched epidermal cell suspension transplantation is an effective, simple and safe method.


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